THERAPEUTIC AREA PORTFOLIO · 49 PRODUCTS
Cardiovascular & Hematology
This portfolio supports anticoagulant and antiplatelet programs, lipid-lowering therapies, heart-failure and cardiomyopathy candidates, and selected hematology programs represented by the catalog’s terminal APIs.
Target APIs & Active Pipeline Programs in Cardiovascular & Hematology
Cardiovascular & Hematology Products (49)
Catalog products related to terminal APIs in this area.
![Chemical structure of 5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-pyridinone](/images/structures/A-01.svg)
CP-APXM-01CAS 545445-44-1
5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-pyridinoneTarget API: Apixaban
![Chemical structure of Ethyl (2Z)-chloro[(4-Methoxyphenyl)hydrazono]ethanoate](/images/structures/A-02.svg)
CP-ATOR-01CAS 125971-94-0
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetateTarget API: Atorvastatin calcium
![Chemical structure of 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide](/images/structures/A-05.svg)
CP-ATOR-03CAS 125971-96-2
2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamideTarget API: Atorvastatin calcium
![Chemical structure of 4-(4-Fluorophenyl)-6-Isopropyl-2-[ (N-Methyl-N-Methylsulfonyl) Amino]Pyrimidine-5-YL-Methanol](/images/structures/A-06.svg)
CP-ROSU-01CAS 147118-36-3
4-(4-Fluorophenyl)-6-Isopropyl-2-[ (N-Methyl-N-Methylsulfonyl) Amino]Pyrimidine-5-YL-MethanolTarget API: Rosuvastatin
![Chemical structure of 5-Methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2- carboxylic acid;hydrochloride](/images/structures/A-07.svg)
CP-EDOX-02CAS 720720-96-7
5-Methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2- carboxylic acid;hydrochlorideTarget API: Edoxaban
![Chemical structure of Ethyl (1S,3R,4R)-4-hydroxy-3-[(2-methylpropan-2-yl) oxycarbonylamino]cyclohexane-1-carboxylate](/images/structures/A-08.svg)
CP-EDOX-04CAS 365997-33-7
Ethyl (1S,3R,4R)-4-hydroxy-3-[(2-methylpropan-2-yl) oxycarbonylamino]cyclohexane-1-carboxylateTarget API: Edoxaban
![Chemical structure of Ethyl 2-[(5-chloropyridin-2-yl)amino]-2-oxoacetate](/images/structures/A-09.svg)
![Chemical structure of Ethyl 2-[(5-chloropyridin-2-yl)amino]-2-oxoacetate; hydrochloride](/images/structures/A-10.svg)
CP-EDOX-03CAS 1243308-37-3
Ethyl 2-[(5-chloropyridin-2-yl)amino]-2-oxoacetate; hydrochlorideTarget API: Edoxaban
![Chemical structure of Tert-butyl N-[(1R,2S,5S)-2-Amino-5-(dimethylcarbamoyl) cyclohexyl]carbamate;oxalic acid](/images/structures/A-11.svg)
CP-EDOX-01CAS 1210348-34-7
Tert-butyl N-[(1R,2S,5S)-2-Amino-5-(dimethylcarbamoyl) cyclohexyl]carbamate;oxalic acidTarget API: Edoxaban
![Chemical structure of Tert-butyl N-[(1R,2S,5S)-2-amino-5-(Dimethylcarbamoyl) cyclohexyl]carbamate](/images/structures/A-12.svg)
A-12CAS 365998-36-3
Tert-butyl N-[(1R,2S,5S)-2-amino-5-(Dimethylcarbamoyl) cyclohexyl]carbamateTarget API: Edoxaban
![Chemical structure of (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one](/images/structures/A-13.svg)
CP-EZET-01CAS 189028-95-3
(4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-oneTarget API: Ezetimibe
![Chemical structure of 4-{[(4-Fluorophenyl)imino]methyl}phenol](/images/structures/A-15.svg)
CP-LERC-01CAS 74936-72-4
5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acidTarget API: Lercanidipine/Nicardipine
CP-MK16-01CAS 908846-88-8
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-fluoro-1H-indol-3-yl)propanoic acidTarget API: MK-0616
CP-MK16-04CAS 94790-24-6
(S)-2-tertButoxycarbonylamino-3-(4-methoxy-phenyl)-propionic acid methyl esterTarget API: MK-0616
![Chemical structure of (6R,10S)-10-Amino-1-(difluoromethyl)-1,4,7,8,9,10-hexahydro-6-methyl-11,15-metheno-15H-pyrazolo[4,3-b][1,7]diazacyclotetradecin-5(6H)-one](/images/structures/A-26.svg)
CP-MILV-01CAS 1802431-24-8
(6R,10S)-10-Amino-1-(difluoromethyl)-1,4,7,8,9,10-hexahydro-6-methyl-11,15-metheno-15H-pyrazolo[4,3-b][1,7]diazacyclotetradecin-5(6H)-oneTarget API: Milvexian（BMS-986177)
CP-MILV-02CAS 2505174-94-5
(R)-6-(4-chloropyridin-2-yl)-6,6-dimethoxy-2-methylhexanoic acidTarget API: Milvexian（BMS-986177)
CP-MILV-03CAS 2499807-81-5
(R)2(difluoromethyl)5methyl2H3aza1(4,2)pyridine2(5,4)pyrazolecyclononane4,9dioneTarget API: Milvexian（BMS-986177)
CP-MILV-04CAS 2505175-03-9
6-(4-Chloro-2-pyridinyl)-6,6-dimethoxy-2-methyl-2-hexenoic acidTarget API: Milvexian（BMS-986177)
CP-MILV-05CAS 1802430-55-2
6-(5-chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl)pyrimidin-4-olTarget API: Milvexian（BMS-986177)
CP-TICA-01CAS 376608-71-8
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium (2R)-hydroxy(phenyl)ethanoateTarget API: Ticagrelor
CP-TICA-02CAS 1156491-10-9
(1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine hydrochlorideTarget API: Ticagrelor
![Chemical structure of 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-ethanol (2R,3R)-2,3-dihydroxybutanedioate](/images/structures/A-35.svg)
CP-TICA-03CAS 376608-65-0
2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-ethanol (2R,3R)-2,3-dihydroxybutanedioateTarget API: Ticagrelor
![Chemical structure of 5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile](/images/structures/A-37.svg)
CP-VERI-01CAS 1350653-26-7
5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrileTarget API: Vericiguat
![Chemical structure of 5-fluoro-1-(2-fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine](/images/structures/A-38.svg)
CP-VERI-02CAS 1350653-24-5
5-fluoro-1-(2-fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridineTarget API: Vericiguat
CP-OBIC-01CAS 261947-64-2
Ethyl (2R,4S)-4-amino-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylateTarget API: Obicetrapib
![Chemical structure of 6-Amino-2,2-Dimethyl-4H-Pyrido [3,2-B] [1,4] Oxazin-3-one](/images/structures/E-23.svg)
CP-FOST-02CAS 1002726-62-6
6-Amino-2,2-Dimethyl-4H-Pyrido [3,2-B] [1,4] Oxazin-3-oneTarget API: Fostamatinib
CP-IPTA-02CAS 1481631-51-9
tert-Butyl 4-formyl-5-methoxy-7-methyl-1H-indole-1-carboxylateTarget API: Iptacopan HCl
CP-VOXE-02CAS 903550-26-5
(tetrahydro-2h-pyran-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-pyrazoleTarget API: Voxelotor
