THERAPEUTIC AREA PORTFOLIO · 33 PRODUCTS
Neuroscience & Pain
The catalog supports non-opioid pain research alongside migraine, sleep, psychiatric and neurodegenerative programs, with terminal APIs ranging from selective ion-channel approaches to established CNS mechanisms.
Target APIs & Active Pipeline Programs in Neuroscience & Pain
Neuroscience & Pain Products (33)
Catalog products related to terminal APIs in this area.
![Chemical structure of 5-Chloro-2-((R)-5-Methyl-[1,4]diazepan-1-yl)benzooxazole hydrochloride](/images/structures/D-09.svg)
CP-SUVO-02CAS 1266664-66-7
5-Chloro-2-((R)-5-Methyl-[1,4]diazepan-1-yl)benzooxazole hydrochlorideTarget API: Suvorexant
CP-CARI-01CAS 189153-10-4
2-(Trans-4-((Tert-Butoxycarbonyl)Amino)Cyclohexyl)Acetic AcidTarget API: Cariprazine
CP-CARI-02CAS 917342-29-1
Tert-Butyl (Trans-4-(2-Hydroxyethyl)Cyclohexyl)CarbamateTarget API: Cariprazine
![Chemical structure of (1R,5S)-3-ethyl-Bicyclo[3.2.0]hept-3-en-6-one](/images/structures/D-19.svg)
![Chemical structure of 3-ethylbicyclo[3.2.0]hept-3-en-6-one](/images/structures/D-20.svg)
CP-SUZE-01CAS 2875066-56-9
(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxypheny)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carboxylic acid Cinchonan-9-ol saltTarget API: Suzetrigine （VX-548）
CP-SUZE-02CAS 2649470-87-9
(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carboxylic acidTarget API: Suzetrigine （VX-548）
CP-SUZE-03CAS 2649470-89-1
(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carboxylic acid (R)-1-phenylethan-1-amine saltTarget API: Suzetrigine （VX-548）
CP-SUZE-04CAS 2875066-49-0
(2S,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-yl 4-nitrobenzoateTarget API: Suzetrigine （VX-548）
CP-SUZE-05CAS 44864-47-3
(R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoic acidTarget API: Suzetrigine （VX-548）
CP-SUZE-06CAS 2875066-35-4
(R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)furan-2(5H)-oneTarget API: Suzetrigine （VX-548）
CP-SUZE-07CAS 2875067-31-3
(R)-4,4,4-trifluoro-3-hydroxy-3-methylbutan-2-oneTarget API: Suzetrigine （VX-548）
![Chemical structure of (2R,3S)-2-{(1R)-1-[3,5-BIS(Trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholine HCl](/images/structures/E-04.svg)
CP-APRE-01CAS 171482-05-6
(2R,3S)-2-{(1R)-1-[3,5-BIS(Trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholine HClTarget API: Aprepitant
![Chemical structure of 5-ChloroMethyl-2,4-dihydro-[1,2,4]triazol-3-one](/images/structures/E-05.svg)
![Chemical structure of 1-(1-(1H-imidazole-1-carbonyl)piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one](/images/structures/H-09.svg)
CP-RIME-01CAS 1373116-06-3
1-(1-(1H-imidazole-1-carbonyl)piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-oneTarget API: Rimegepant
![Chemical structure of 2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride](/images/structures/H-10.svg)
CP-RIME-02CAS 781649-84-1
2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochlorideTarget API: Rimegepant
![Chemical structure of 7,8-dihydro-5H-cyclohepta[b]pyridine-5,9(6H)-dione](/images/structures/H-11.svg)