THERAPEUTIC AREA PORTFOLIO · 39 PRODUCTS
Metabolic & Endocrine
Driven by the catalog’s GLP-1, incretin, SGLT2 and DPP-4 programs, this area brings together intermediates for established diabetes therapies and emerging oral or peptide-based approaches to obesity and metabolic disease.
Target APIs & Active Pipeline Programs in Metabolic & Endocrine
Metabolic & Endocrine Products (39)
Catalog products related to terminal APIs in this area.
CP-ALEN-02CAS 2212021-51-5
1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-5-(tetrahydro-2H-pyran-4-yl)-1Hindole-2-carboxylic acidTarget API: Aleniglipron
![Chemical structure of Tert-butyl(S)-3-(3-(4-(diethylphosphoryl)-3-(methylamino)phenyl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxyla](/images/structures/B-03.svg)
CP-ALEN-03CAS 2685825-07-2
Tert-butyl(S)-3-(3-(4-(diethylphosphoryl)-3-(methylamino)phenyl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylaTarget API: Aleniglipron
CP-SGLT-01CAS 32384-65-9
2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactoneTarget API: Canagliflozin/Dapagliflozin/Empagliflozin
![Chemical structure of (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan](/images/structures/B-08.svg)
CP-EMPA-03CAS 915095-94-2
(3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furanTarget API: Empagliflozin
CP-EMPA-04CAS 1360568-68-8
(5-bromo-2-chlorophenyl)(4-hydroxyphenyl)MethanoneTarget API: Empagliflozin
![Chemical structure of (Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OSu](/images/structures/B-21.svg)
CP-SEMA-04CAS 1118767-16-0
(S)-22-(Tert-butoxycarbonyl)-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontane-1,41-dioic acidTarget API: Semaglutide
CP-SEMA-05CAS 560088-89-3
10-Oxo-5,8,14,17-tetraoxa-2,11-diazanonadecanedioic acid 1-(9H-fluoren-9-ylmethyl) esterTarget API: Semaglutide
![Chemical structure of Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OH](/images/structures/B-26.svg)
![Chemical structure of 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a] pyrazine hydrochloride](/images/structures/B-28.svg)
CP-SITA-02CAS 762240-92-6
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a] pyrazine hydrochlorideTarget API: Sitagliptin
CP-SITA-03CAS 486460-00-8
BOC-(R)-3-amino-4-(2,4,5-trifluoro-phenyl)-butyric acidTarget API: Sitagliptin
CP-ORFO-02CAS 2212021-83-3
5-((S)-2,2-dimethyltetrahydro2H-pyran-4-yl)-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro1,2,4-oxadiazol-3-yl) cyclopropyl)-1H-indole-2- carboxylic acidTarget API: Orforglipron
![Chemical structure of 5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 3-amino-2-(4-fluoro-3,5-dimethylphenyl)-2,4,6,7-tetrahydro-4-methyl-, 1,1-dimethylethyl ester, (4S)-](/images/structures/B-36.svg)
CP-ORFO-03CAS 2212021-59-3
5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 3-amino-2-(4-fluoro-3,5-dimethylphenyl)-2,4,6,7-tetrahydro-4-methyl-, 1,1-dimethylethyl ester, (4S)-Target API: Orforglipron
![Chemical structure of tert-Butyl (S)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-3-(2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate](/images/structures/B-37.svg)
CP-ORFO-04CAS 2212021-61-7
tert-Butyl (S)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-3-(2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylateTarget API: Orforglipron
![Chemical structure of (S)-3-[4-[(5-bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran](/images/structures/CP-EMPA-02.svg)
CP-EMPA-02CAS 915095-89-5
(S)-3-[4-[(5-bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuranTarget API: Empagliflozin
